Journal Club 2011

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Thalidomide in bleeding vascular malformations:

CT Colonoscopy as a triage tool after positive fecal blood tests:


Switching from Infliximab to Adalimumab: is it save?

  • Van Assche G et al.: Switch to adalimumab in patients with Crohn’s disease controlled by maintenance infliximab: prospective randomised SWITCH trial. Gut 2011 [ahead of print].

Proton pump Inhibitors, do they affect the Efficaty of Aspirin:

Charlot M et al.: Protonpumpinhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched study. BMJ 2011 [ahead of print]


Aspirin lowers risk of colorectal cancer in patients with lynch syndrome

  • Burn J et al.: Long-term eff ect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet 2011, Published Online October 28.

High Fiber Diet Does Not Protect Against Asymptomatic Diverticulosis:


Adenocarcinoma among Patients with Barrett’s Esophagus:

Rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection:

Garey KW et al.: A randomized, double-blind, placebo-controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection. J Antimicrob Chemother 2011 Sep 21. [Epub ahead of print].


Early versus Late Parenteral Nutrition in Critically Ill:

Dextranomer to Treat Faecal incontinence

  • Graf et al.: Efficacy of dextranomer in stabilised hyaluronic acid for treatment of faecal incontinence: a randomised, sham-controlled trial. Lancet 2011; 377:997–1003.


Adalimumab for induction of remission in active ulcerative colitis

Reinisch W et al.: Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut 2011;60:780-87.

Predictors for Neoplastic Progression in Barrett's Esophagus:

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