Chicken Journal club (Bible hour)

Paper Schedule 2013


Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon.

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

ß-adrenergic stimulation increases macrophage CD14 expression and E. coli phagocytosis through PKA signaling mechanisms

The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct

CRISPR-Cas systems for editing, regulating and targeting genomes

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

Flow cytometry APC-tandem dyes are degraded through a cell-dependent mechanism

Symbiotic bacteria direct expression of an intestinal bactericidal lectin.

A direct PCR approach to accelerate analyses of human-associated microbial communities

Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine

Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells (HT29-C1.16E)

Bacterial translocation from the gastrointestinal tract of athymic (nu/nu) mice

Graphical Perception: Theory, Experimentation, and Application to the Development of Graphical Methods

Graphical perception and graphical methods for analyzing scientific data

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity

Characterization of diet-dependent metabolic serotypes: analytical and biological variability issues in rats

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site

Differential secretion of cytokines

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

Molecular analysis of commensal host-microbial relationships in the intestine

Autoantigen recognition is required for recruitment of IGRP(206-214)-autoreactive CD8+ T cells but is dispensable for tolerance

Simultaneous amplification and detection of specific DNA sequences

Systems biology: a brief overview

Spectrophotometer: new instrument for ultrarapid cell analysis

High-throughput sequencing of the zebrafish antibody repertoire

Requirement for RORgamma in thymocyte survival and lymphoid organ development.

Unresponsiveness of MyD88-deficient mice to endotoxin

Interleukin-6: possible biological roles during exercise

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut

Rapid secretion of interleukin-1beta by microvesicle shedding

Points of significance: Power and sample size

Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

Adaptive immune features of natural killer cells

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

Microbiota-mediated colonization resistance against intestinal pathogens

B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation

Crohn's disease

Cytotoxic T-cell memory without antigen

T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria

Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria

Retinoic acid imprints gut-homing specificity on T cells

The role of the immune system in governing host-microbe interactions in the intestine

Commensal bacteria at the interface of host metabolism and the immune system

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.

Control of early viral and bacterial distribution and disease by natural antibodies

Sequencing technologies - the next generation

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

Eosinophils: changing perspectives in health and disease

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut

Enterotypes of the human gut microbiome

Non-haemolytic beta-amino-acid oligomers

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies

Previously discussed papers (2011-2012)

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

T cell receptor antagonist peptides induce positive selection

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

T cell tolerance by clonal elimination in the thymus

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS)

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)

The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes

The origin and antigen-dependent distribution of IgA-containing cells in the intestine

Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions

Continuous cultures of fused cells secreting antibody of predefined specificity

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis

H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus

Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles

The covalent structure of an entire gamma G immunoglobulin molecule (1969)