Journal Club 2017

Monday, Nov. 27th, 2017 - Olivier Schären

Maternal IgG immune complexes induce food allergen-specific tolerance in offspring

Salt-responsive gut commensal modulates TH17 axis and disease

Monday, Nov. 27th, 2017 - Olivier Schären

An Oxidative Central Metabolism Enables Salmonella to Utilize Microbiota-Derived Succinate

Respiration of Microbiota-Derived 1,2-propanediol Drives Salmonella Expansion during Colitis

Monday, Nov. 14th, 2017 - Mercedes Gomez

A single-cell survey of the small intestinal epithelium

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors

Friday, Nov. 10th, 2017 - Bahti Yilmaz

CHOP-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury

Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice

Monday, Oct. 30th, 2017 - Bahti Yilmaz

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

Monday, Oct. 23rd, 2017 - Anna Wenning

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine

IL-17-Secreting γδ T Cells Are Completely Dependent upon CCR6 for Homing to Inflamed Skin

Monday, Oct. 16th, 2017 - Jakob Zimmermann

Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation

A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development

Monday, Oct. 6th, 2017 - Li Hai

Commensal bacteria make GPCR ligands that mimic human signalling molecules

Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins.

Monday, Sep. 25th, 2017 - Bahti Yilmaz

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals

Monday, Sep. 22nd, 2017 - Catherine Mooser

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

The intestinal microbiota regulates body composition through NFIL3 and the circadian clock

Monday, Sep. 4th, 2017 - Olivier Schären

Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of Salmonella Typhimurium via Inflammatory Monocytes

Interleukin-10 Production by T and B Cells Is a Key Factor to Promote Systemic Salmonella enterica Serovar Typhimurium Infection in Mice

Monday, Aug. 10th, 2017 - Mercedes Gomez

The aryl hydrocarbon receptor controls cell-fate decisions in B cells

Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells

Friday, July. 7th, 2017 - Julien

Identifying specificity groups in the T cell receptor repertoire

Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis

Monday, June. 26th, 2017 - Olivier

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Friday, June. 2nd, 2017 - Hai Li

Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Friday, May. 19th, 2017 - Jakob

Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease

Cooperating Commensals Restore Colonization Resistance to Vancomycin-Resistant Enterococcus faecium

Friday, May. 12th, 2017 - Mercedes

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

Mapping the human DC lineage through the integration of high-dimensional techniques

Friday, May. 5th, 2017 - Anna

Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin

Feedback control of AHR signalling regulates intestinal immunity

Friday, April. 28th, 2017 - Catherine

High-avidity IgA protects the intestine by enchaining growing bacteria

Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens

Friday, March. 24th, 2017 - Francesca

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

Low-dose penicillin exposure in early life decreases Th17 and the susceptibility to DSS colitis in mice through gut microbiota modification

Friday, March. 17th, 2017 - Marcel

Microbiota-induced obesity requires farnesoid X receptor

The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction

Friday, March. 10th, 2017 - Nicolas

Faecal microbiota transplantation protects against radiation-induced toxicity

Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission

Friday, Feb. 24th, 2017 - Stephanie

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

Mining the Human Gut Microbiota for Immunomodulatory Organisms

Friday, Feb. 17th, 2017 - Julien

Dynamics of the human gut microbiome in inflammatory bowel disease

Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis

Friday, Feb. 10th, 2017 - Bahti

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions

Monday, Jan. 9th, 2017 - Hai Li

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease

Persistent microbiome alterations modulate the rate of post-dieting weight regain