Journal Club 2019

Friday, Dec. 13th, 2019 - Francesca Ronchi

Light-entrained and Brain-Tuned Circadian Circuits Regulate ILC3s and Gut Homeostasis

Vaginal Microbiome Transplantation in Women With Intractable Bacterial Vaginosis


Friday, Nov. 25th, 2019 - Hai Li

Human Gut Bacteria Contain Acquired Interbacterial Defence Systems

Bacteriophage Targeting of Gut Bacterium Attenuates Alcoholic Liver Disease


Monday, Oct. 21th, 2019 - Cristina Kalbermatter

MAIT Cells Are Imprinted by the Microbiota in Early Life and Promote Tissue Repair

The Intestinal Microbiota Programs Diurnal Rhythms in Host Metabolism Through Histone Deacetylase 3


Friday, Oct. 11th, 2019 - Ian Young

Fc Glycan-Mediated Regulation of Placental Antibody Transfer

Ruminococcus gnavus, a Member of the Human Gut Microbiome Associated With Crohn's Disease, Produces an Inflammatory Polysaccharide


Friday, Sep. 30th, 2019 - Steven Misztal

Decreased Maternal Serum Acetate and Impaired Fetal Thymic and Regulatory T Cell Development in Preeclampsia

Elevated Faecal 12,13-diHOME Concentration in Neonates at High Risk for Asthma Is Produced by Gut Bacteria and Impedes Immune Tolerance


Anna Wenning

Human Placenta Has No Microbiome but Can Contain Potential Pathogens


Friday, August. 16th, 2019 - Hai Li

T Cell-Mediated Regulation of the Microbiota Protects Against Obesity

Laboratory Mice Born to Wild Mice Have Natural Microbiota and Model Human Immune Responses


Friday, July. 5th, 2019 - Jakob Zimmermann

Quantifiable Predictive Features Define Epitope-Specific T Cell Receptor Repertoires

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells


Friday, June. 28th, 2019 - Steven Misztal

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

Mucispirillum Schaedleri Antagonizes Salmonella Virulence to Protect Mice Against Colitis


Friday, May. 24th, 2019 - Yuan Dong

Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium Difficile Infection

Microbiotas From Humans With Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt + Regulatory T Cells and Exacerbate Colitis in Mice


Friday, May. 10th, 2019 - Francesca Ronchi

Compartmentalized Gut Lymph Node Drainage Dictates Adaptive Immune Responses

Single-cell Transcriptomes of the Regenerating Intestine Reveal a Revival Stem Cell


Monday, April. 26th, 2019 - Anna Wenning

Early Life Stress Disrupts Intestinal Homeostasis via NGF-TrkA Signaling

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium


Monday, March. 29th, 2019 - Bahtiyar Yilmaz

Commensal Enterobacteriaceae Protect against Salmonella Colonization through Oxygen Competition

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice


Monday, March. 18th, 2019 - Cristina Kalbermatter

The epigenetic control of stemness in CD8+ T cell fate commitment

Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis


Monday, March. 15th, 2019 - Jakob Zimmermann

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria

Interleukin-22 protects intestinal stem cells against genotoxic stress


Hai Li

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

BCR-dependent lineage plasticity in mature B cells


Friday, March. 1st, 2019 - Francesca Ronchi

GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease


Monday, Feb. 8th, 2019 - Tim Rollenske

Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10

Identification of preexisting adaptive immunity to Cas9 proteins in humans


Monday, Jan. 21st, 2019 - Disha Tandon

Alterations in the diversity and composition of mice gut microbiota by lytic or temperate gut phage treatment

Gnotobiotic mouse model of phage-bacterial host dynamics in the human gut


Monday, Jan. 18th, 2019 - Julien Limenitakis

Host immunoglobulin G selectively identifies pathobionts in pediatric inflammatory bowel diseases

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes


Monday, Jan. 7th, 2019 - Anna Wenning

PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs

The gut microbiome is required for full protection against acute arsenic toxicity in mouse models